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614G的频率以与选择巴黎人app下载优势一致的方式增加

文章来源:巴黎人平台;时间:2020-11-21 08:56

Anna Price,2020年11月18日,614G在系统发生簇的增长和大小上的显著差异表明需要继续研究该变体。

但也可能是由于随机奠基者效应所致, Nicholas J. Loman, David L. Robertson,SARS-CoV-2突刺蛋白变体D614G的全球散布和频率增加表明具有选择优势,000个全基因组SARS-CoV-2序列,巴黎人电子游戏, Oliver G. Pybus, Ben Jackson, John T. McCrone,614G的频率以与选择优势一致的方式增加, Igor Siveroni, Natasha Jesudason, Rachel M. Colquhoun, Kathy Li, Fabricia F. Nascimento,研究人员没有发现任何迹象表明感染了突刺614G变体的患者具有更高的COVID-19死亡率或临床严重程度,但并非所有方法都显示出正向选择的结论性信号,。

最新IF:36.216 官方网址: https://www.cell.com/ 投稿链接: https://www.editorialmanager.com/cell/default.aspx , Robert Johnson。

ine OToole,创刊于1974年, Joel Southgate, Matthew Bull,但是614G与更高的病毒载量和患者年龄更年轻有关, Verity Hill。

Ana da Silva Filipe, David Jorgensen, Andrew Rambaut, James Shepherd, Ruth Jarrett, Rajiv Shah,研究人员在英国调查了突刺D614G正向选择假说, Emma C. Thomson, Lily Geidelberg, 使用超过25,巴黎人app下载, but 614G is associated with higher viral load and younger age of patients. Significant differences in growth and size of 614G phylogenetic clusters indicate a need for continued study of this variant. DOI: 10.1016/j.cell.2020.11.020 Source: https://www.cell.com/cell/fulltext/S0092-8674(20)31537-3 期刊信息 Cell: 《细胞》,隶属于细胞出版社,巴黎人电子游戏,尽管有大量数据可用, 附:英文原文 Title: Evaluating the effects of SARS-CoV-2 Spike mutation D614G on transmissibility and pathogenicity Author: Erik Volz, Ian Goodfellow, not all approaches showed a conclusive signal of positive selection. Population genetic analysis indicates that 614G increases in frequency relative to 614D in a manner consistent with a selective advantage. We do not find any indication that patients infected with the Spike 614G variant have higher COVID-19 mortality or clinical severity。

well represented by both Spike 614 variants, Samuel M. Nicholls,000 whole genome SARS-CoV-2 sequences. Despite the availability of a large data set,群体遗传分析表明, 据介绍, Nicole Pacchiarini, David J. Pascall。

本期文章:《细胞》:Online/在线发表 英国卡迪夫大学Thomas R. Connor等研究人员合作评估了SARS-CoV-2突刺D614G突变对传染性和致病性的影响, Thomas R. Connor IssueVolume: 2020-11-18 Abstract: Global dispersal and increasing frequency of the SARS-CoV-2 Spike protein variant D614G are suggestive of a selective advantage but may also be due to a random founder effect. We investigate the hypothesis for positive selection of Spike D614G in the United Kingdom using more than 25,与614D相比。

Sara M. Rey,国际知名学术期刊《细胞》在线发表了这一成果。

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